Mytocel MSK / Rigenera
Auricular cartilage biopsy; mechanical disaggregation only. No culture, enzyme digestion or ex-vivo expansion. Prepared during the clinical sitting.
For medical professionals
A cartilage operation, redesigned as a needle-delivered protocol.
NanoACi is a surgeon-led, point-of-care technique combining mechanically prepared autologous cartilage micrografts, a cell-free collagen matrix and autologous PRF before intra-articular needle delivery in one sitting.
Register professional interestWorking definition
Protocol—not a new manufactured product.
The intellectual value sits in patient selection, preparation sequence, ratios, timing, delivery and post-procedure care—the reproducible technique as a whole.
NANon-Arthroscopic
No arthroscopic access is used for delivery.
NNeedle-Delivered
Image-guided delivery by an appropriately trained surgeon.
OOne-Stage
Harvest, preparation, combination and delivery in one sitting.
ACAutologous Chondrogenic
Autologous tissue selected for a cartilage-supporting biological intent.
iinjection
The lower-case “i” distinguishes injection from conventional implantation.
Technique architecture
Cells. Matrix. Signal.
Separate components, brought together at point of care under a defined surgical protocol.
ChondroFiller® liquid
Cell-free native type I collagen matrix supplied in a two-chamber syringe, forming a hydrogel after component mixing.
Vivostat® PRF
Patient-derived platelet-rich fibrin providing a fibrin carrier with platelets and a controlled growth-factor release profile.
Same patientSame sittingNo storageNo culture
Scientific position
Component evidence is the foundation. NanoACi-specific evidence is the next task.
Published literature supports the individual technologies and the broader concepts of autologous micrografting, collagen scaffolds and platelet-rich fibrin. It does not yet answer every question about this exact combined technique.
The correct next step is not to overstate the conclusion. It is to measure the protocol prospectively, publish it and allow scrutiny.
Review the evidence map100
Founding outcomes programme
One hundred consecutive cases. One transparent dataset.
NanoACi 100 is designed as a prospective, consecutive-case programme with a locked protocol, baseline imaging and standardised patient-reported outcome collection.
Protocol lockConsecutive enrolmentFollow-upPublish
Diagnosis, grade, imaging, prior treatment and patient goals.
Joint, preparation variables, delivery details and protocol deviations.
Pain, function, quality of life, satisfaction, return to activity and safety.
Consistent follow-up milestones, with longer-term data continuing beyond publication.
Build the network
Refer. Observe. Research. Learn.
Professional interest is open to surgeons, sports physicians, radiologists, physiotherapists and research collaborators who want to follow the evidence or explore future training.
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